2025 ABD Stock Exchange Most Gaining and Losing Stocks

Winners and Losers in the US Stock Market in 2025

The year 2025 drew attention due to the expansion of artificial intelligence trading in the US stock markets and the leadership of chip stocks in the S&P 500. Shares of companies building data centers also experienced significant growth. However, the economic uncertainty caused by tariffs imposed by President Donald Trump put pressure on the stocks of some companies.

Prominent companies were particularly those engaged in data storage. Here are the biggest winners and losers of 2025 based on the data:

Winner: New AI Leadership

Technology stocks, especially those connected to artificial intelligence, regained market dominance in 2025. Giants like Microsoft, Amazon, Alphabet, and Meta collectively committed to invest over $440 billion to enhance their AI capabilities. These developments led companies like Sandisk, Western Digital, and Seagate Technology to rank among the best performers in the S&P 500.

Winner: Newly Added Companies to the S&P 500

The year 2025 was marked by the inclusion of many companies like Robinhood Markets, Sandisk, AppLovin, and Carvana into the S&P 500 index. Each of these companies achieved triple-digit percentage gains, placing them among the top 20 of the index.

Winner: Palantir

Shares of Palantir are set to achieve triple-digit gains for the third consecutive year, a success attributed to strong support from retail investors.

Winner: Warner Bros. Discovery

Warner Bros. Discovery estimated to have gained approximately 175% in value in 2025 due to acquisition speculation. When the company was put up for sale, it received offers from Paramount and Netflix; the board considered Netflix’s offer.

Loser: Consumer Staples

Economic uncertainty and the impact of tariffs negatively affected the stocks of major consumer staples companies. Clorox, Lamb Weston Holdings, Campbell's, and Constellation Brands were among the worst performers in the S&P 500.

Loser: Retail Sector

The same uncertainty also affected the stocks of Deckers Outdoor, owner of the brands Hoka and Ugg; the company ended a nine-year streak of growth, losing approximately 50% in value in 2025. Shares of Lululemon Athletica are also expected to drop by 45%.

Loser: Managed Healthcare

Health insurance stocks performed poorly in 2025 despite potential changes brought by policies of the Trump administration. Shares of Molina Healthcare lost over 40% in value, while UnitedHealth Group and Centene Corp. also experienced declines of more than 30%.